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2023-10-30 13:51阅读:
2008年8月26日,星期二,晴、夜转阵雨
翻译Helen传来的林小姐所发来的一封信。这是我在奥运会结束后所作的第一件译作。译文如下:
Aug. 25, 2008
Miss Lin,
Nucleoside drug is the generic term of a class of drugs, including lamivudine, famciclovir, adefovir and entacavir. The drug they asked should belong to such class of drugs.
Lamivudine is the earliest nucleoside drug in clinical application and has gradually been washed out due to producing drug resistance. On the basis of lamivudine and modifYing the chemical constitution, some new drugs have been produced, such as famciclovir, adefovir and entacavir. Yet owing to their lacunas and hence they can not overcome the shortcoming of virus variation, drug fast and end-of-dose failure, in addition, the course of treatment become longer and longer and the majority of patients have to take them in their lifetimes. In fact, there are a lot of limitations in the usage of such drugs in their cradle lands of European and American countries which are extremely cautious to ev
aluation of the curative effect of these drugs. Many international pharmaceuticals companies hope to search drug with high safety to replace such drugs, which is the reason why Doctor Martin of Sanofi Company gives high evaluation to JingYuqinggan Capsules.
Compared with nucleoside drug, JingYuqinggan Capsules has the following strong points:
(1) Short Course of Treatment: The course of treatment of nucleoside drug is 1-3 years and the majority of patients have to take them in their lifetimes. The course of treatment of JingYuqinggan Capsules is 3 months achieving treatment results of antivirus better than nucleoside drug.
(2) No Recurrence: The peculiarity of nucleoside drug’s action is “can’t stop in application and recurrence in stopping”. The follow-up results after withdrawal shows no recurrence after withdrawal.
(3) No Virus Variation: Variation is the fatal weakness of nucleoside drug. There is no any report of virus variation regarding nucleoside drug as a traditional Chinese medicine at the modern time, the reason is its influence on virus is multi-target and all-round. Nucleoside drug only influences one of them, such as YMDD, very readily to initiate variation.
(4) Multi-effects: The single-target action of nucleoside drug determines the peculiarity of its single effect. In addition to restraining virus, JingYuqinggan Capsules protects liver, is anti-inflammatory and regulates immunity; the patients can receive the treatment fully.
Therefore, with its positive effects of curing chronic hepatitis B, JingYuqinggan
Capsules is a safe and effective pharmaceutics of the traditional Chinese medicine at the modern time (Invention patent certificate No: ZL200510116890.3) with antivirus as the main action, improving immunity of organism, protecting liver and improving symptoms and physical signs, and it can fully replace nucleoside drug.
Li Qiushi

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