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多动症儿童的好消息:Ω-3脂肪酸有效

2011-09-09 07:55阅读:
补充Ω-3脂肪酸可以缓解多动症和注意力缺陷的儿童的症状。2011年8月美国儿童级青少年心理协会杂志报道了一项荟萃分析的结果 (一种将全球主要的研究结果进行集中分析的数理统计方法)。

文章分析了包括699名注意力缺陷儿童在内的10项研究,发现服用Ω-3脂肪酸的儿童症状的严重程度有明显改善,虽然改善程度较小。服用大剂量二十碳五烯酸(一种Ω-3脂肪酸,英文缩写EPA)的儿童也显示同样效果。

负责该研究的耶鲁大学医学院儿童研究中心的教授对该结果页深感意外,原来一直认为保健品的效果非常有限,起效也非常漫长。作者最后仍然提醒患者:研究结果证实Ω-3脂肪酸效果比较温和,疗效与现用的其他药物仍然有差距,因此不能误认为Ω-3脂肪酸可以替代现用药物,但是Ω-3脂肪酸的副作用很少,因此可以作为理想的辅助用药,对于中度症状的患儿更是一个理想的选择。


September 8, 2011 — Supplementation with omega-3 fatty acid may decrease symptoms of attention-deficit/hyperactivity disorder (ADHD) in children, a new meta-analysis suggests.
In an evaluation of 10 trials with 699 total children with ADHD, investigators found that those who received omega-3 supplements had a 'small but significant' improvement in symptom severity compared with those who were given placebo. This effect was also significant in the children who received suppl
ements that specifically contained higher doses of eicosapentaenoic acid.
'I was actually expecting this treatment to not be effective at all, that we shouldn't expect much from a nutritional supplement that often takes a while to work. So the results were a surprise to me,' lead author Michael H. Bloch, MD, assistant professor at the Yale Child Study Center at Yale University School of Medicine in New Haven, Connecticut, told Medscape Medical News.
'However, I would hope that nobody thinks the take-home message is that omega-3s are the answer for everyone in lieu of traditional medications,' said Dr. Bloch.
In fact, the investigators note that the relative efficacy of this treatment 'was modest compared with currently available pharmacotherapies for ADHD, such as psychostimulants, atomoxetine, or a2 agonists.'
Still, because of its 'relatively benign side-effect profile,' they write, omega-3 supplements may be a reasonable add-on to traditional interventions or an option for families who do not want other psychopharmacologic treatments.
'I think the medication treatments we currently have for ADHD work best. But omega-3 represents a potentially safer alternative, especially in mild cases,' said Dr. Bloch.
The study was published online August 16 in the Journal of the Academy of Child and Adolescent Psychiatry.

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